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Project Summary in brief

Introduction to COMT History : Axelrod et al. (1958) first described the enzyme-catalyze O-methylation of catecholamines and other catechols in the late 1950s. The enzyme responsible for the O-methylation, catechol-O-methyltransferase (COMT; E.C. 2.1.1.6), was partly purified and characterized by the same group. Role : Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade … Continue reading

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